Zopiclone should be taken orally by mouth for 50 to 60 minutes before going to bed, or as your doctor or nurse tells you to. It typically takes one hour for this medication to work as a sleep aid. The tablet should not be split or chewed. Take the tablet in its entirety instead. As squashing the tablet can influence the viability of the prescription. Zopiclone 7.5 mgcan be taken with or without food, depending on the user's preference.